Thyroid is a butterfly shaped gland located in the front of the neck.
Laboratory determination of thyroid profile function is useful in distinguishing patients with euthyroid ( normally functional thyroid gland) from those with hyperthyroidism or hypothyroidism.
The function of the thyroid gland is to take iodine from circulating blood, combine it with amino acid tyrosine and convert it to thyroid hormones T3 and T4.
70-80% of thyroid hormone is transported in bound form, however it is the free hormone FT3 and FT4 which becomes the true determinant of thyroid status of the patient.
Evaluation of thyroid profile status is not a simple procedure as it does not depend solely on the measurement of circulating thyroid hormone , hence apart from Total T3 and T4; TSH ,serum FT3 and FT4 along with Protein thyroid binding globulin (TBG) and thyroid auto antibodies are also suggested.
Thyroid auto antibodies can play havoc with the finely tuned systems functional within the body. Many people particularly women are afflicted with thyroid disorders.
Adolescent girls ,women with menstrual cycle irregularities, PCOD should get TSH level s checked regularly.
Pregnant women should regularly monitor TSH and those with known hypothyroidism must undergo estimation of FT3 and FT4, TSH levels periodically as it might lead to poor mental , development of the growing foetus as the foetus is dependent on maternal thyroid profile during first 3 months of gestation.
Rising trends of congenital hypothyroidism is seen in Paediatric population. A timely diagnosis, treatment and monitoring thyroid hormone status shall definitely help in appropriate mental and physical well being of the child.
Thyroid hormone at molecular level controls many physiological functions and fine tunes them.
Keep thyroid profile levels in check.